Griffith University

Carrie Lovitt

Name: Carrie Lovitt
Position: Research Fellow
Research Area: Breast Cancer
Qualifications: BSc (Hons), PhD

Biography: Carrie obtained her Bachelor of Science with Honours from Monash University in 2007. In 2008, she joined the Discovery Biology laboratory as a Research Assistant, working in the malaria group.  She completed her Doctor of Philosophy with Discovery Biology in the field of breast cancer, specifically designing 3D cell culture models. Her degree conferred in March 2014. Following her PhD, Carrie was employed as a Research Fellow working on a drug discovery research project studying breast and pancreatic cancer. In July 2016, Carrie joined the Cancer Therapeutics CRC team, a joint commercial academic partnership. Carrie’s cancer research involves on the development of 2D and 3D in vitro cell culture models suitable for HTS/HCS and employing these cancer cell culture models in early stage drug discovery screening programs. In addition, she conducts in-depth evaluation of potential anti-cancer agents and interrogates chemotherapeutic drug resistance mechanisms.

Discovery Biology:

Publications:

Hoffman AF, Simpson KJ, Horvath P, Lovitt C, Silver S, Easton E, LaBarbera DV, Mendez M, Rothenberg ME, Seldin J, Wardwell-Swanson J, Fennell M. SBI2 HCS/HCA 3D Imaging: Best Practices and Unmet Needs Colloquium. ASSAY and Drug Development Technologies. 2017 Jan; 15(1): 1-7.

Bhatia M, Lovitt CJ, Raninga PV, Avery VM, Di Trapani G and Tonissen KF. Expression of the thioredoxin system is modulated by the in vivo-like cancer cell environment upon auranofin treatment. European Journal of Cell Biology. 2016 Oct; 95(10): 378-388.

Lovitt C,  Shelper T and  Avery VM. Cancer Drug Discovery: Recent Innovative Approaches to Tumor Modeling. Expert Opinion On Drug Discovery. [Invited review] 2016 Sep; 11(9):885-894.

Shelper TB, Lovitt CJ and Avery VM. Assessing Drug Efficacy in a Miniaturized Pancreatic Cancer in vitro 3D Cell Culture Model. ASSAY and Drug Development Technologies. [Special edition] 2016 Sep; 14(7): 367-380.

Lovitt CJ, Hilko DH, Avery VM and Poulsen SA. Development of ethynyl-2′-deoxyuridine chemical probes for cell proliferation. Bioorganic & Medicinal Chemistry.  2016 Sep 15; 24(18):4272-4280.

Lovitt CJ, Shelper TB and Avery VM. Evaluation of chemotherapeutics in a three-dimensional breast cancer model. Journal of Cancer Research and Clinical Oncology. 2015 May; 141(5): 951-959.

Lovitt CJ, Shelper TB and Avery VM. Advanced cell culture techniques for cancer drug discovery. Biology. [invited review] 2014 May 30; 3(2): 345-367.

Hoque Md T, * Windus LC, * Lovitt CJ and Avery VM. PCa Analyser: A 2D-Image Analysis Based Module for Effective Determination of Prostate Cancer Progression in 3D Culture. PLoS One. 2013 Nov 20; 8(11): e79865. * Equal first author.

Lovitt CJ*, Shelper TB* and Avery VM. Miniaturized three-dimensional cancer model for drug evaluation.  ASSAY and Drug Development Technologies. 2013 September 1; 11(7): 435-448.  * Equal first author.

Yu M, Price JR, Jensen P,  Lovitt CJ, Shelper T, Duffy S, Windus LC, Avery VM, Rutledge PJ and Todd MH. Copper, Nickel, and Zinc Cyclam-Amino Acid and Cyclam-Peptide Complexes may be Synthesized with “Click” Chemistry and Are Noncyctotoxic. Inorg Chem. 2011 Dec 19; 50(24): 12823-12835.

COMMITTEES AND PANELS

  • 2017: Serve on the Student Poster Competition judging panel at the Society of Laboratory Automation and Screening 6th International Conference and Exhibition.
  • 2016 – present: Serve on the Society for Laboratory Automation and Screening Student and Early Career Professional Advisory Committee.
  • 2016 – present: Serve on the European Association of Cancer Research Image of the Month Review Panel.
  • 2015 – 2016: Served on the American Association of Cancer Research Associate Member Council-led Program Committee.

 AWARDS

Scholarship/University Awards:

  • 2016: Griffith University 3Rs Award recipient.
  • 2014: Nominated for the Chancellor’s Medal, Griffith University.
  • 2009: Australian Postgraduate Award.
  • 2009: Cancer Therapeutics CRC Top Up Scholarship.

 Conference/General Awards:

  • 2016: Prize winner in the Society for Laboratory Automation and Screening Academic Poster Competition.
  • 2016: Finalist in the Journal of Laboratory Automation & Journal of Biomolecular Science Art of Science Contest.
  • 2015: First prize in the Eskitis Institute for Drug Discovery, Griffith University Photography Competition.
  • 2012: First prize (Best Method category) in the Journey through Science Day poster competition hosted by the New York Academy of Sciences and PepsiCo, New York USA.
  • 2011: Second prize in the Australian Society for Medical Research Postgraduate Student Conference poster competition, Brisbane Australia.

Travel Awards:

  • Tony B. Academic Travel Award to attend the Society of Laboratory Automation and Screening 6th International Conference and Exhibition; Washington DC, USA (February 2017).
  • Cancer Therapeutics CRC Award to attend the Oncology Drug Development in Practice course; Amsterdam, Netherlands (November 2016).
  • Interstate Travel Award sponsored by Custom Science to attend the Functional High Throughput Technologies Meeting; Melbourne, Australia (October 2016).
  • Society of Biomolecular Imaging and Informatics Award to attend the Society of Biomolecular Imaging and Informatics. Boston, USA (September 2016).
  • PerkinElmer to attend the Society of Biomolecular Imaging and Informatics. Boston, USA (September 2016).
  • Tony B. Academic Travel Award to attend the Society of Laboratory Automation and Screening 5th International Conference and Exhibition; San Diego, USA (January 2016).
  • European Association of Cancer Research to attend the 23rd Biennial Congress of the EACR; Munich, Germany (July 2014).
  • PerkinElmer to attend the 104thAmerican Association for Cancer Research Annual Meeting; Washington, D.C., USA (April 2013).
  • New York Academy of Sciences (NYAS) and PepsiCo to attend the December Career Day at the NYAS; New York, USA (December 2012).
  • ASN Events Australia to attend the 24th Lorne Cancer Conference; Victoria, Australia (February 2012).
  • Cold Spring Harbor Laboratory to attend the Automated Imaging & High-Throughput Phenotyping Meeting; Cold Spring Harbor Laboratory, New York, USA (April 2012).
  • Cancer Council Queensland to attend the 103rd American Association of Cancer Research Annual Meeting; Chicago, USA (April 2012).
  • Griffith University to attend the 103rd American Association of Cancer Research Annual Meeting; Chicago, USA (April 2012).

  CONFERENCES

  • Lovitt, CJ; Shelper, TB; Avery, VM. HCS/HCA Data and Informatics Special Interest Group session, Society of Laboratory Automation and Screening 6th International Conference and Exhibition; Washington D.C., USA (Invited Oral; February 2017).
  • Lovitt, CJ; Hilko, DH; Avery, VM; Poulsen, SA. Society of Laboratory Automation and Screening 6th International Conference and Exhibition; Washington D.C., USA (Poster; February 2017).
  • Lovitt, CJ; Shelper, TB; Avery, VM. Brisbane Life Science ECR Symposium. Brisbane, Australia (Oral; December, 2016).
  • Lovitt, CJ; Shelper, TB; Avery, VM. Functional High Throughput Technologies Meeting. Melbourne, Australia (Invited oral; October 2016).
  • Lovitt, CJ; Shelper, TB; Avery, VM. Society of Biomolecular Imaging and Informatics. Boston, USA (Invited Discussion Leader for the ‘3D Models’ session of the 3D Imaging: Best Practices and Unmet Needs Colloquium; September 2016).
  • Lovitt, CJ; Shelper, TB; Avery, VM. Society of Laboratory Automation and Screening 5th International Conference and Exhibition; San Diego, USA (Poster; January 2016).
  • Lovitt, CJ; Avery, VM. 23rd Biennial Congress of the European Association of Cancer Research; Munich, Germany (Poster; July 2014). European Journal of Cancer: Volume 50, Suppl. 5, S23–S242.
  • Lovitt, CJ; Avery, VM. 104th American Association of Cancer Research Annual Meeting; Washington, D.C., USA (Poster; April 2013). Cancer Research: Volume 73, Issue 8, Supplement 1.
  • Lovitt, CJ; Avery, VM. December Career Day at the New York Academy of Sciences (NYAS); New York City, New York, USA (Poster; December 2012).
  • Lovitt, CJ; Shelper, TB; Avery, VM. Cold Spring Harbor Laboratory Automated Imaging & High-Throughput Phenotyping Meeting; Cold Spring Harbor Laboratory, New York, USA (Poster; April 2012).
  • Lovitt, CJ; Avery, VM. 103rd American Association of Cancer Research Annual Meeting; Chicago, Illinois, USA (Poster; March-April 2012). Cancer Research: Volume 72, Issue 8, Supplement 1.
  • Lovitt, CJ; Avery, VM. Cancer Therapeutics CRC Postgraduate Research Symposium; Melbourne, Australia (Oral; October 2012).
  • Lovitt, CJ; Avery, VM. Eskitis Student Symposium at the Eskitis Institute for Drug Discovery; Brisbane, Australia (Oral; May 2012).
  • Lovitt, CJ; Avery, VM. 24th Lorne Cancer Conference; Victoria, Australia (Poster; February 2012).
  • Lovitt, CJ; Avery, VM. Cancer Therapeutics CRC Postgraduate Research Symposium; Melbourne, Australia (Poster; November 2011).
  • Lovitt, CJ; Avery, VM. Cell and Developmental Biology Meeting; Brisbane, Australia (Poster; October 2011).
  • Lovitt, CJ; Avery, VM. Cancer Therapeutics CRC Postgraduate Research Symposium; Melbourne, Australia (Poster; November 2011).
  • Lovitt, CJ; Avery, VM. Australian Society for Medical Research (ASMR) Postgraduate Student Conference; Brisbane, Australia (Poster; May 2011).
  • Lovitt, CJ; Avery, VM. Cancer Therapeutics CRC Postgraduate Research Symposium; Melbourne, Australia (Poster; October 2010).

Other: Monash University

Publications:

Kennan RM, Lovitt CJ, Han X, Parker D, Turnbull L, Whitchurch CB, Rood JI. (2015). A two-component regulatory system modulates twitching motility in Dichelobacter nodosus. Vet Microbiol, 179(1-2): 34-41.

Scholarship/University Awards:

  • Vacation Scholarship in the Faculty of Medicine, Nursing and Health Sciences (Monash University, 2007).
  • Top student award for the subject Anatomy: Organs, Tissues and Body Systems (Monash University, 2005).

Conferences:

Honours Degree of Bachelor of Science

  • Kennan, RM; Lovitt, CJ; Whitchurch, CB; Turnbull, L; Han, X; Rood; JI. Prato Conference on the Pathogenesis of Bacterial Diseases in Animals, Italy (2010).